赵冶,副教授,毕业于澳大利亚悉尼大学医学院,博士,硕士生导师。现任四川省国际医学交流促进会人工智能与肿瘤专业委员会委员。近年来主持国家级课题及横向课题等5项,中国中医药医学促进会科技进步奖一等奖;四川省海外高层次留学人才。
● 研究兴趣、领域:
1、肿瘤转移及耐药机制;
2、细胞死亡调节肾纤维化机制;
● 研究项目(近五年)
1、横向项目,PD-1抗体对PBMC细胞的影响,成医合(2023)787号,2023/12-2025/01,在研,主持
2、横向项目,啤酒花黄酮抑制小鼠肾纤维化的体内研究,成医合(2020)397号,2020/10-2021/12,结题,主持
3、四川省科技厅2020年度科技创新及科学普及培训项目,基于多源异构数据的慢性疾病合理用药科教管理创新平台,2020JDKP0083,2020/01-2021/12,40万,结题,参与
4、四川省科技厅应用基础重点项目,OXM1/Dishevelled/Snail信号轴介导EMT诱发非小细胞肺癌转移及耐药的机制研究,2019YJ0370,2019/01-2022/01,结题,参与
5、国家自然科学基金青年基金项目,31701212,鸢尾素介导的线粒体自噬改善糖尿病肾病的作用及机制研究,2018/01-2020/12,24万元,已结题,主持。
● 代表性论文:
Zhao Y(#), Liu Y(#), Liao R, Ran P, Liu Y, Li Z, Shao J, Zhao L. Biofilm Microenvironment-Sensitive Piezoelectric Nanomotors for Enhanced Penetration and ROS/NO Synergistic Bacterial Elimination.ACS applied materials & interfaces2024 Jan 24;16(3):3147-3161. doi: 10.1021/acsami.3c15689. Epub 2024 Jan 11.
Mingbo Wu(#),, Wenwu Ling,(#), Jiaojun Wei(#), Ran Liao, Haiyue Sun, Dongqiu Li,Ye Zhao(*), Long Zhao(*),Biomimetic photosensitizer nanocrystals trigger enhanced ferroptosis for improving cancer treatment,Journal of Controlled Release,Volume 352,2022,Pages 1116-1133,ISSN 0168-3659,https://doi.org/10.1016/j.jconrel.2022.11.026.
Yin L(#), Yang YH(#), Zhu WL(#), Xian Y, Han ZY, Huang HY, Peng LT, Zhang K(*),Zhao Y(*).(2021). Heat Shock Protein 90 Triggers Multi-Drug Resistance of Ovarian Cancer via AKT/GSK3 beta/beta-Catenin Signaling. Front Oncol, 2021. 11: p. 620907.
Huang, Y.Q., Zeng, H., Chen, L.Y., Luo, Y.L., Ma, X.L.(*), andZhao, Y(*). (2021). Exploration of an Integrative Prognostic Model of Radiogenomics Features With Underlying Gene Expression Patterns in Clear Cell Renal Cell Carcinoma. Front Oncol, 2021. 11: p. 640881.
Ye Zhao(#), Xi Qiao(#), Thian Kui Tan, Hong Zhao, Yun Zhang, Lixin Liu, Jianlin Zhang, LihuaWang, Qi Cao, YipingWang, YaWang, Yuan MinWang, VincentW.S. Lee, Stephen I Alexander, David C.H. Harris and Guoping Zheng(*).Matrix metalloproteinase 9-dependent Notch signaling contributes to kidney fibrosis through peritubular endothelial-mesenchymal transition. Nephrology Dialysis Transplantation, 2017, 32 (5): 781-791.
Ye Zhao(#), Xi Qiao(#), Lihua Wang, Tian Kui Tan, Hong Zhao, Yun Zhang, Jianlin Zhang, Padmashree Rao, Qi Cao, Yiping Wang, Ya Wang, Yuan Min Wang, Vincent W. S. Lee, Stephen I. Alexander, David C. H. Harris and Guoping Zheng(*).Matrix metalloproteinase 9 induces endothelial-mesenchymal transition via Notch activation in human kidney glomerular endothelial cells.
● 荣誉、奖励及参加学术团体的情况:
中国中医药医学促进会科技进步奖;成都医学院教学进步奖,四川省海外高层次留学人才。全国大学生生命竞赛创新创业类二等奖。
● 电话:028-62739567
E-mail:zhaoye525@cmc.edu.cn